rpsR [Fri Jan 29 2016 17:19:36 GMT+0100 (CET)]

ribosomal protein

locus: BSU40890

pI: 11.00

mw: 8.00 kDa

function: translation

product: ribosomal protein S18

essential: yes

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|essential genes]

This gene is a member of the following [SW|regulons]

• [SW|ComK regulon], [SW|stringent response]

Gene

Coordinates on the chromosome (coding sequence): 4,198,603 -> 4,198,842

Phenotypes of a mutant

• essential [Pubmed|23002217,12682299]

The protein

Protein family

• [SW|ribosomal protein] S18P family (according to Swiss-Prot)

[SW|Interactions]

• [protein|search|RpsF]-[protein|search|RpsR], the heterodimer binds the structure in the ''[protein|search|rpsF]'' mRNA 5' UTR [Pubmed|24310371]

Expression and Regulation

Operon

• ''[protein|search|yyaF]-[protein|search|rpsF]-[protein|search|ssbA]-[protein|search|rpsR]'' [Pubmed|14762004]
• ''[protein|search|rpsF]-[protein|search|ssbA]-[protein|search|rpsR]'' [Pubmed|24310371,22383849]

[SW|Sigma factor]

• ''[protein|search|rpsF]'': [protein|search|SigA] [Pubmed|24310371]

Regulation

• [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
• [protein|search|ComK]: transcription activation [Pubmed|11948146]

References

• 12884008,14762004,11948146,19653700,11948165,23002217,22383849,24310371