cydA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

cytochrome bd ubiquinol oxidase (subunit I), high affinity terminal oxidase

locus: BSU38760

pI: 8.94

mw: 52.00 kDa

function: respiration

product: cytochrome bd ubiquinol oxidase (subunit I), high affinity terminal oxidase

essential: no

synonyms: yxkK

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.1|Terminal oxidases]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|respiration], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|CcpA regulon], [SW|ResD regulon], [SW|Rex regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,977,791 -> 3,979,197

The protein

Catalyzed reaction/ biological activity

• Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|YthA]

[SW|Cofactors]

• contains an iron-sulfur cluster

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|cydA]-[protein|search|cydB]-[protein|search|cydC]-[protein|search|cydD]'' [Pubmed|16207915]

Regulation

• repressed by glucose ([protein|search|CcpA])
• induced under anaerobic conditions ([protein|search|Rex]) [Pubmed|16207915]
• expressed under anaerobic conditions ([protein|search|ResD]) [Pubmed|17322317]

Regulatory mechanism

• [protein|search|CcpA]: transcription repression
• [protein|search|Rex]: transcription repression [Pubmed|15231791]
• [protein|search|ResD]: transcription activation [Pubmed|17322317]

References

• 16207915,17322317,17015645,15231791,9852001,10551842,15231791,17322317