purT [Mon Aug 31 2015 13:52:08 GMT+0200 (CEST)]

phosphoribosylglycinamide formyltransferase 2

locus: BSU02230

pI: 4.72

mw: 41.00 kDa

function: purine biosynthesis

product: phosphoribosylglycinamide formyltransferase 2

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.1|Biosynthesis/ acquisition of purine nucleotides]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of nucleotides]

The protein

Catalyzed reaction/ biological activity

• Formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate (according to Swiss-Prot)

Protein family

• ATP-grasp domain (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|PurK]

Structure

• [PDB|1KJ9] (with Mg-ATP from ''Escherichia coli'', 55% identity, 69% similarity) [Pubmed|11953435]

Expression and Regulation

Operon

• ''purT'' (according to [http://dbtbs.hgc.jp/COG/prom/purT.html DBTBS])

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|7496533]

References

• 7496533