infA [Mon Jan 18 2016 18:46:41 GMT+0100 (CET)]

translation initiation factor IF-1

locus: BSU01390

pI: 7.00

mw: 8.00 kDa

function: translation

product: initiation factor IF-1

essential: yes

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.11|Translation factors]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.7|Phosphorylation on a Tyr residue]

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|essential genes], [SW|phosphoproteins]

This gene is a member of the following [SW|regulons]

• [SW|stringent response]

Gene

Coordinates on the chromosome (coding sequence): 147,585 -> 147,803

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Protein family

• S1-like domain (according to Swiss-Prot)

Modification

• phosphorylation on Tyr-60 [Pubmed|17218307]

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Regulation

• [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]

References

• 8635744,17218307