hxlA [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

3-hexulose-6-phosphate synthase

locus: BSU03460

pI: 4.56

mw: 22.00 kDa

function: ribulose monophosphate pathway for formaldehyde fixation

product: 3-hexulose-6-phosphate synthase

essential: no

ec: 4.1.2.43

synonyms: yckG

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[SW|Categories] containing this gene/protein

• [SW|resistance against oxidative and electrophile stress]

This gene is a member of the following [SW|regulons]

• [SW|HxlR regulon]

Gene

Coordinates on the chromosome (coding sequence): 375,166 -> 375,798

The protein

Catalyzed reaction/ biological activity

• D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde (according to Swiss-Prot)

Protein family

• HPS subfamily (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|hxlA]-[protein|search|hxlB]'' [Pubmed|10572115]

Regulation

• induction by formaldehyde ([protein|search|HxlR]) [Pubmed|10572115]

Regulatory mechanism

• transcription activation by [protein|search|HxlR] [Pubmed|10572115]

References

• 10572115,16428816,19170879