SubtiBank SubtiBank
yxaM
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yxaM

similar to antibiotic resistance protein
locus
BSU_39930
pI
8.31
mw
44.59 kDa
protein length
399 aa Sequence Blast
gene length
1200 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    4,101,166 → 4,102,365

    The protein

    Protein family

  • [SW|major facilitator superfamily] (according to UniProt)

    • [SW|Localization]

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|787BB72119DB1321A8281D7C46FED28CAEDBC97C|yxbB]-[gene|88B01CC87394AEE693A98574F9343EBF99F0D60E|yxbA]-[gene|A15368CD02487EBC1AF999FED34672E38167BCB2|yxnB]-[gene|9446D9C88CBBBC5A08495D8AA49A92A9F47F2C9B|asnH]-[gene|BF0E188249161B3CC24D223FDD48B820EBED8F55|yxaM]
    description
    [Pubmed|10746760]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|20185509], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [Pubmed|12618455], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|15101989], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • repressed by glucose (8-fold) [Pubmed|12850135]
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    Biological materials

    Mutant

  • MGNA-B688 (yxaM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1687 NBRP B. subtilis, Japan]
  • BKE39930 (Δ[gene|BF0E188249161B3CC24D223FDD48B820EBED8F55|yxaM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCGGAAAACGAATAAAAGA, downstream forward: _UP4_TAAATGTTTTGTATCACAGT
  • BKK39930 (Δ[gene|BF0E188249161B3CC24D223FDD48B820EBED8F55|yxaM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCGGAAAACGAATAAAAGA, downstream forward: _UP4_TAAATGTTTTGTATCACAGT

    • References

  • 10746760,10498721,12618455,15101989