uvrX [2019-05-21 18:23:48]

UV-damage repair protein

Locus: BSU21500

Isoelectric point: 9.63

Molecular weight: 46.57 kDa

Protein length: 416 aa

Gene length: 1251 bp

Function: DNA repair after UV damage

Product: UV-damage repair protein

Essential: no

Synonyms: yolE

Genomic Context

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Categories containing this gene/protein

• Information processing → Genetics → DNA repair/ recombination
• Information processing → Genetics → DNA repair/ recombination → Other proteins
• Prophages and mobile genetic elements → Prophages → SP-beta prophage

Gene

Coordinates: 2,270,407 → 2,271,657

The protein

Protein family

• DNA polymerase type-Y family (according to UniProt)

Paralogous protein(s)

• PolY1, PolY2

Expression and Regulation

Operons

• Genes: yolD-uvrX
  Description: PubMed

  Regulatory mechanism

  • LexA: repression, PubMed, in LexA regulon

  Regulation

  • induced by DNA damage (LexA) PubMed

Biological materials

Mutant

• BKE21500 (ΔuvrX::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AATCAATCATTGTATGTAAC, downstream forward: _UP4_TAAGATAAATTTAAACTTAT
• BKK21500 (ΔuvrX::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AATCAATCATTGTATGTAAC, downstream forward: _UP4_TAAGATAAATTTAAACTTAT

References

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