uvrX

UV-damage repair protein

locus: BSU_21500

pI: 9.63

mw: 46.57 kDa

protein length: 416 aa

gene length: 1251 bp

function: DNA repair after UV damage

product: UV-damage repair protein

essential: no

synonyms: yolE

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
• [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage]

Gene

Coordinates: 2,270,407 → 2,271,657

The protein

Protein family

• [SW|DNA polymerase type-Y family] (according to UniProt)

Paralogous protein(s)

• [protein|C87D33852F263A553CA747608E6200E4AD8344B5|PolY1], [protein|F0BC150F59730E64BA9AB3F979544EF6B5CC4E9E|PolY2]

[SW|Domains]

• [SW|UmuC domain] (aa 12-196) (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|A9D5625FF5F1A3845FF6F8A290F647CCA73D39EF|yolD]-[gene|BE8D5E038C0FD748C0F9C3F18DCA601BFFE8EA52|uvrX]
  description: [Pubmed|16267290]

  regulatory mechanism

  • [protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|16267290], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]

  regulation

  • induced by DNA damage ([protein|search|LexA]) [Pubmed|16267290]

Biological materials

Mutant

• BKE21500 (Δ[gene|BE8D5E038C0FD748C0F9C3F18DCA601BFFE8EA52|uvrX]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21500 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AATCAATCATTGTATGTAAC, downstream forward: _UP4_TAAGATAAATTTAAACTTAT
• BKK21500 (Δ[gene|BE8D5E038C0FD748C0F9C3F18DCA601BFFE8EA52|uvrX]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21500 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AATCAATCATTGTATGTAAC, downstream forward: _UP4_TAAGATAAATTTAAACTTAT

References

• 16267290,30916324