pbpG [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

penicillin-binding protein 2d

locus: BSU37510

pI: 9.00

mw: 71.00 kDa

function: bifunctional glucosyltransferase/ transpeptidase

product: penicillin-binding protein 2d

essential: no

synonyms: ywhE

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.7|Penicillin-binding proteins]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|cell wall synthesis], [SW|sporulation proteins], [SW|membrane proteins], [SW|penicillin-binding proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigF regulon], [SW|SigG regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,849,818 -> 3,851,893

The protein

[SW|Localization]

• cell membrane (according to Swiss-Prot)
• prespore [http://www.ncbi.nlm.nih.gov/sites/entrez/15758244 Link to a summary]

Expression and Regulation

Operon

• ''pbpG'' [Pubmed|22383849]

[SW|Sigma factor]

• [protein|search|SigF], [protein|search|SigG] [Pubmed|16497325,15758244,10767540]

Regulation

• expressed during sporulation in the forespore ([protein|search|SigF], [protein|search|SigG]) [Pubmed|16497325,15758244,10767540]

Additional information

• A [protein|search|ncRNA] is predicted between '[protein|search|pbpG]' and '[protein|search|ywhD]' [PubMed|20525796]

Biological materials

two-hybrid system

• ''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([SW|BACTH]), available in [SW|Jeff Errington] lab

References

• 16497325,11567005,10767540,20525796