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yfmD [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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yfmD [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

iron/citrate ABC transporter (permease)
locus
BSU07510
pI
9.00
mw
34.00 kDa
function
iron uptake
product
iron/citrate ABC transporter (permease)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.5|Uptake of iron/ siderophores]
  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.1|ABC transporters for the uptake of iron/ siderophores]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.4|ABC transporters for the uptake of iron/ siderophores]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|Fur regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    824,714 -> 825,715

    The protein

    Protein family

  • FecCD subfamily (according to Swiss-Prot)
  • Structure

  • [PDB|4G1U] (from ''Yersinia pestis'', the [SW|YfmD]-[SW|YfmE]-[SW|YfmF] complex, 34% identity) [Pubmed|23142986]
  • [SW|Localization]

  • cell membrane [Pubmed|10092453]
  • [SW|Interactions]

  • [protein|search|YfmF]-([protein|search|YfmD]-[protein|search|YfmE])-([protein|search|YfmC]-[protein|search|YhfQ]) [Pubmed|10092453]
  • Expression and Regulation

    Operon

  • ''[protein|search|yfmC]-[protein|search|yfmD]-[protein|search|yfmE]-[protein|search|yfmF]'' [Pubmed|16672620]
  • Regulation

  • induced upon iron starvation ([protein|search|Fur]) [Pubmed|16672620,12354229]
  • Regulatory mechanism

  • [protein|search|Fur]: transcription repression [Pubmed|16672620,12354229]
  • References

  • 10092453,16672620,12354229,23142986