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yybP [2017-8-11 16:0:3]
membrane protein, may be involved in manganese detoxification
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
4,169,166 → 4,169,612
The protein
Structure
[PDB|3LLL] (from the mouse, 28% identity) [pubmed|20471395][SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operons
genes
[gene|BD3A3D84AD3A21B634B8EBAF684B690FE02BD857|yybP]
description
[Pubmed|25794618]
regulatory mechanism
[regulon|yybP-ykoY motif|yybP-ykoY motif]: antitermination, in the presence of the ligand Mn2+ [Pubmed|25794618], in [regulon|yybP-ykoY motif|yybP-ykoY motif]regulation
induced in the presence of Mn2+ ([SW|yybP-ykoY motif]) [Pubmed|25794618]the [SW|RNA switch] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]view in new tabBiological materials
Mutant
MGNA-B838 (yybP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1837 NBRP B. subtilis, Japan]References
15096624,25794618,25794619,20471395