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hutP
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hutP

transcriptional antiterminator of the hut operon
Locus
BSU_39340
Isoelectric point
6.06
Molecular weight
16.43 kDa
Protein length
151 aa Sequence Blast
Gene length
456 bp Sequence Blast
Function
regulation of histidine utilization
Product
transcriptional antiterminator
Essential
no
Synonyms
hutP1

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
4,041,483 → 4,041,938

The protein

Protein family

  • hutP family (single member, according to UniProt)
  • Cofactors

  • Mg2+ PubMed
  • Effectors of protein activity

  • HutP binds its RNA target to cause antitermination in the presence of histidine PubMed
  • Structure

  • 3BOY (complex bound to the hut mRNA), 1WPT
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon
  • CodY: repression, PubMed, in CodY regulon
  • HutP: antitermination, at a protein-dependent RNA switch located between hutP and hutH PubMed, in HutP regulon
  • Regulation

  • induced by histidine (HutP) PubMed
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    Biological materials

    Mutant

  • BKE39340 (ΔhutP::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGAATCACTCAATTCC, downstream forward: _UP4_TGAAACAGCCCATAGATCTT
  • BKK39340 (ΔhutP::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGAATCACTCAATTCC, downstream forward: _UP4_TGAAACAGCCCATAGATCTT
  • References

    Reviews

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    Research papers

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