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treP [2017-05-09 15:36:36]
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treP [2017-05-09 15:36:36]

trehalose-specific phosphotransferase system, EIIBC component of the PTS
Locus
BSU07800
Isoelectric point
8.56
Molecular weight
49.84 kDa
Protein length
470 aa Sequence Blast
Gene length
1410 bp Sequence Blast
Function
trehalose uptake and phosphorylation
Product
trehalose-specific phosphotransferase system, EIIBC component
Essential
no
E.C.
2.7.1.69
Synonyms
treB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → Phosphotransferase system → Sugar specific PTS proteins
  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of trehalose
  • Groups of genes → Membrane proteins
  • Groups of genes → Phosphoproteins → Phosphorylation on a Cys residue

    • Gene

    Coordinates
    850,367 → 851,779

    The protein

    Catalyzed reaction/ biological activity

  • Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)

    • Protein family

  • PtsI permease, sucrose permease (Scr) family PubMed

    • Localization

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    treP-treA-treR
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • TreR: repression, PubMed, in TreR regulon
  • CcpA: repression, PubMed, in CcpA regulon
  • PhoP: activation, PubMed, in PhoP regulon

    • Regulation

  • expressed under conditions of phosphate limitation (PhoP) PubMed
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    Biological materials

    Mutant

  • MGNA-C259 (treP::erm), available at the NBRP B. subtilis, Japan

    • References

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