yodC [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

NADH oxidase

locus: BSU19550

pI: 5.00

mw: 22.00 kDa

function: regeneration of NAD from NADH

product: NADH oxidase

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.4|Electron transport/ other/ based on similarity]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[SW|Categories] containing this gene/protein

• [SW|electron transport/ other], [SW|resistance against oxidative and electrophile stress]

This gene is a member of the following [SW|regulons]

• [SW|YodB regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,127,813 -> 2,128,421

The protein

Catalyzed reaction/ biological activity

• regeneration of NAD from NADH [Pubmed|26312069]

Protein family

• type A lantibiotic family (according to Swiss-Prot)

Structure

• [PDB|3GE6] (from '' Exiguobacterium sibiricum'', 42% identity)

Expression and Regulation

Regulation

• induced by thiol-reactive compounds (catechol, menaquinone) ([protein|search|YodB]) [Pubmed|18208493]

Regulatory mechanism

• [protein|search|YodB]: transcription repression [Pubmed|18208493]

References

• 17407181,18208493,26312069