flhF [Mon Aug 31 2015 13:54:20 GMT+0200 (CEST)]

signal recognition particle-like GTPase, placement and assembly of flagella, control of basal body position

Locus: BSU16400

Isoelectric point: 8.00

Molecular weight: 40.00 kDa

Function: placement and assembly of polar flagella

Product: signal recognition particle-like GTPase

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Exponential and early post-exponential lifestyles → Motility and chemotaxis → Flagellar proteins
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

• CodY regulon, DegU regulon, SigD regulon, Spo0A regulon

Gene

Coordinates on the chromosome (coding sequence): 1,709,747 -> 1,710,847

The protein

Catalyzed reaction/ biological activity

• GTPase activity PubMed
• placement of the first flagellar protein, FliF PubMed

Protein family

• GTP-binding SRP family (according to Swiss-Prot)

Effectors of protein activity

• interaction with FlhG activates the GTPase activity of FlhF PubMed

Structure

• 2PX3 (complexed with GTP-Mg2) PubMed
• 3SYN (complex with its activator YlxH) PubMed

Localization

• cell membrane (according to Swiss-Prot)

Interactions

• FlhG-FlhF (FlhG binds the GTP-bound homodimer of FlhF) PubMed

Expression and Regulation

Operon

• part of the [[fla-che operon]]
• flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed
• ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed

Sigma factor

• flgB: SigA PubMed, SigD PubMed
• ylxF: SigD PubMed

Regulation

• see [[fla-che operon]]

Regulatory mechanism

• see [[fla-che operon]]

Biological materials

Mutant

• 1A925 ( flhF::cat), PubMed, available at BGSC

References

Reviews

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Original Publications

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