glnH [Thu Mar 24 2016 11:34:08 GMT+0100 (CET)]

glutamine ABC transporter (binding protein)

Locus: BSU27440

Isoelectric point: 8.00

Molecular weight: 29.00 kDa

Function: glutamine uptake

Product: glutamine ABC transporter (binding protein)

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → ABC transporters → Importers → Uptake of amino acids
• Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation
• Metabolism → Amino acid/ nitrogen metabolism → Utilization of amino acids → Utilization of glutamine/ glutamate
• Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• ABC transporters, biosynthesis/ acquisition of amino acids, glutamate metabolism, utilization of amino acids, membrane proteins, sporulation proteins

This gene is a member of the following regulons

• SigE regulon, TnrA regulon

Gene

Coordinates on the chromosome (coding sequence): 2,803,108 -> 2,803,929

The protein

Structure

• 2V25 (from Campylobacter jejuni, 37% identity) PubMed

Localization

• attached to the membrane via GlnM-GlnP PubMed

Interactions

• GlnQ-(GlnM-GlnP)-GlnH PubMed

Expression and Regulation

Operon

• glnQ-glnH-glnM-glnP PubMed

Sigma factor

• SigE PubMed

Regulation

• expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
• expressed during sporulation (SigE) PubMed

Regulatory mechanism

• TnrA: transcription activation PubMed

Biological materials

Mutant

• GP734 (spc), available in the Stülke lab

References

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