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yumC [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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yumC [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

ferredoxin/flavodoxin-NAD(P) oxidoreductase
locus
BSU32110
pI
5.00
mw
36.00 kDa
function
redox reactions that involve ferredoxin and flavodoxin
product
ferredoxin/flavodoxin reductase
essential
yes
ec
1.18.1.2
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.3|Electron transport/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • [SW|Categories] containing this gene/protein

  • [SW|electron transport/ other], [SW|essential genes]

    • Gene

    Coordinates on the chromosome (coding sequence)
    3,301,586 -> 3,302,584

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • 2 reduced ferredoxin or flavodoxin NADP H = 2 oxidized ferredoxin or flavodoxin NADPH (according to Swiss-Prot)

    • Protein family

  • ferredoxin-NADP reductase type 2 family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|YcgT]

    • Modification

  • active site Cys85 is S-bacillithiolated by NaOCl stress in ''B. subtilis'' and other ''Bacillus'' species [http://www.ncbi.nlm.nih.gov/pubmed/22938038 PubMed]

    • [SW|Cofactors]

  • FAD [Pubmed|20878669]

    • Structure

  • [PDB|3LZW] [Pubmed|20878669]

    • [SW|Interactions]

  • dimeric protein [Pubmed|20878669]
  • [protein|search|YumC]-[protein|search|YkuN] (electron transfer from NADPH via [protein|search|YumC] to [protein|search|YkuN]) [Pubmed|25194416]

    • Expression and Regulation

    Operon

  • ''[SW|yumC]'' [Pubmed|22383849]

    • References

  • 22938038,20208166,20878669,19162251,15252706,24529496,25194416,25698107,26507228,26965753