single-strand DNA-specific exonuclease
product
single-strand DNA-specific exonuclease
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication][category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins][category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.6|DNA repair/ recombination/ based on similarity][category|SW 6|Groups of genes] → [category|SW 6.11|Efp-dependent proteins][SW|Categories] containing this gene/protein
[SW|DNA repair/ recombination]This gene is a member of the following [SW|regulons]
[SW|stringent response], [SW|Efp-dependent proteins]Gene
Coordinates on the chromosome (coding sequence)
2,823,419 -> 2,825,779
Phenotypes of a mutant
''[protein|search|recO] [protein|search|recJ]'' double mutants are extremely sensitive against DNA damaging agents [Pubmed|26001966]The protein
Protein family
recJ family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|YorK][SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[protein|search|SsbA]-[protein|search|RecJ] [Pubmed|21170359]Expression and Regulation
Operon
''[protein|search|recJ]-[protein|search|apt]'' [Pubmed|15241682]Regulation
[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]Additional information
[protein|search|translation] is likely to require [protein|search|Efp] due to the presence of several consecutive proline residues [PubMed|23239624,23239623]Biological materials
Mutant
GP895 (''[protein|search|recJ]''::''kan''), available in [SW|Jörg Stülke]'s labBKE27620 (''[protein|search|recJ]''::''erm'', available in the BGSC, in [SW|Fabian Commichau]'s, and in [SW|Jörg Stülke]'s labs)References
Reviews
Original publications
15241682,11948165,10498723,21170359,21205011,26001966 
