SubtiBank SubtiBank
yerC
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yerC

similar to Trp repressor of S. aureus
locus
BSU_06580
pI
4.85
mw
11.89 kDa
protein length
104 aa Sequence Blast
gene length
315 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]

    • Gene

    Coordinates
    716,431 → 716,745

    Phenotypes of a mutant

  • inactivation of ''[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]'' reduces sporulation efficiency to 10% that of wild type cells [Pubmed|26735940]

    • The protein

    Structure

  • [PDB|3KOR] (Trp repressor of Staphylococcus aureus, 67% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|BE1F7BA77CE8B6A1A2D22F31421C27F2E954816A|yerB]-[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: activation, [Pubmed|14651647], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon]

    • regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]
    • view in new tab

    genes
    [gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]-[gene|BE1F7BA77CE8B6A1A2D22F31421C27F2E954816A|yerB]-[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]
    description
    [pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • MGNA-A924 (yerC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/924 NBRP B. subtilis, Japan]
  • BKE06580 (Δ[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE06580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GCGTAATTTATCGATTTGCA, downstream forward: _UP4_TAAAAAACCGCCCTGCCGTC
  • BKK06580 (Δ[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK06580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GCGTAATTTATCGATTTGCA, downstream forward: _UP4_TAAAAAACCGCCCTGCCGTC

    • References

  • 26735940