yxjF [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

sporulation protein, 3-hydroxybutyrate dehydrogenase

locus: BSU38970

pI: 7.00

mw: 27.00 kDa

function: 3-hydroxybutyrate utilization

product: 3-hydroxybutyrate dehydrogenase

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
• [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

[SW|Categories] containing this gene/protein

• [SW|utilization of specific carbon sources], [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|CcpA regulon], [SW|SigE regulon]

Gene

Coordinates on the chromosome (coding sequence): 4,000,539 -> 4,001,312

The protein

Protein family

• short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|hbuT]-[protein|search|scoA]-[protein|search|scoB]-[protein|search|yxjF]'' [Pubmed|10746760]

[SW|Sigma factor]

• [protein|search|SigE] [Pubmed|12662922]

Regulation

• repressed by glucose (4-fold) ([protein|search|CcpA]) [Pubmed|12850135,10666464]
• expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|12662922]

Regulatory mechanism

• [protein|search|CcpA]: transcription repression [Pubmed|12850135,10666464]

Biological materials

Mutant

• GP1112 (spc), available in [SW|Stülke] lab

References

• 16672620,10666464,12850135,10746760,12662922