catD [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

essential for viability in the presence of catechol

locus: BSU08230

pI: 10.12

mw: 14.00 kDa

function: viability in the presence of catechol

product: unknown

essential: no

synonyms: yfiD

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|resistance against oxidative and electrophile stress], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|CatR regulon], [SW|YodB regulon]

Gene

Coordinates on the chromosome (coding sequence): 897,588 -> 897,992

The protein

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|catD]-[protein|search|catE]'' [Pubmed|16872404]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|20639328]

Regulation

• strong induction by diamide and quinones (such as catechol) ([protein|search|YodB], [protein|search|CatR]) [Pubmed|16872404,20639328]

Regulatory mechanism

• [protein|search|YodB]: transcription repression [Pubmed|20639328]
• [protein|search|CatR]: transcription repression [Pubmed|20639328]

References

• 17407181,16872404,20639328