arsB [Mon Aug 31 2015 13:55:44 GMT+0200 (CEST)]

extrusion of arsenite

locus: BSU25790

pI: 9.77

mw: 38.00 kDa

function: detoxification of arsenate and arsenite

product: arsenite exporter

essential: no

synonyms: yqcL

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.11|Resistance against toxic metals]
• [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.3|Skin element]

syns: yqcL

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|resistance against toxic metals], [SW|Skin element]

This gene is a member of the following [SW|regulons]

• [SW|ArsR regulon], [SW|SigF regulon]

The protein

Protein family

• ACR3 family (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|arsR]-[protein|search|yqcK]-[protein|search|arsB]-[protein|search|arsC]'' [Pubmed|9537360]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|9537360], [protein|search|SigF] [Pubmed|16497325]

Regulation

• expressed early during sporulation in the forespore ([protein|search|SigF]) [Pubmed|16497325]
• expressed in the presence of toxic metal ions (As(III), Cd(II) and Ag(I)) ([protein|search|ArsR]) [Pubmed|9537360]

Regulatory mechanism

• [protein|search|ArsR]: transcription repression [Pubmed|9537360]

References

• 9537360,16497325,9537360