SubtiBank SubtiBank
yqjD
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yqjD

propionyl-CoA carboxylase
Locus
BSU_23920
Isoelectric point
9.09
Molecular weight
55.12 kDa
Protein length
507 aa Sequence Blast
Gene length
1524 bp Sequence Blast
Function
lipid metabolism
Product
propionyl-CoA carboxylase
Essential
no
E.C.
6.4.1.3
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
2,486,813 → 2,488,336

The protein

Catalyzed reaction/ biological activity

  • ATP + hydrogencarbonate + propanoyl-CoA --> (S)-methylmalonyl-CoA + ADP + H+ + phosphate (according to UniProt)
  • Protein family

  • AccD/PCCB family (with AccD and YngE, according to UniProt)
  • Paralogous protein(s)

    Domains

  • CoA carboxyltransferase N-terminal domain (aa 1-254) (according to UniProt)
  • CoA carboxyltransferase C-terminal domain (aa 256-501) (according to UniProt)
  • Structure

  • 1VRG (from Thermotoga maritima, 57% identity)
  • Biological materials

    Mutant

  • MGNA-C387 (yqjD::erm), available at the NBRP B. subtilis, Japan
  • BKE23920 (ΔyqjD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTTCGTGTAAAAATGATCCA, downstream forward: _UP4_CTTTAATATGGAGGGACTTA
  • BKK23920 (ΔyqjD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTTCGTGTAAAAATGATCCA, downstream forward: _UP4_CTTTAATATGGAGGGACTTA
  • References

    Research papers

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