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divIB [Wed Feb 24 2016 14:01:37 GMT+0100 (CET)]
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divIB [Wed Feb 24 2016 14:01:37 GMT+0100 (CET)]

cell-division initiation protein (septum formation)
locus
BSU15240
pI
9.00
mw
30.00 kDa
function
septum formation
product
cell-division protein
essential
yes
synonyms
dds, tms-12

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|cell division], [SW|sporulation proteins], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|essential genes], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigE regulon], [SW|SigM regulon], [SW|SpoIIID regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,593,704 -> 1,594,495

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Protein family

  • ftsQ family (according to Swiss-Prot)
  • Structure

  • [PDB|2ALJ] (major extracytoplasmic domain, Geobacillus stearothermophilus)
  • [SW|Localization]

  • cell membrane [Pubmed|9426141]
  • [SW|Interactions]

  • [protein|search|PbpB]-[SW|DivIB]-([protein|search|FtsL]-[SW|DivIC])2 [Pubmed|20870765], as part of the [SW|divisome]
  • [protein|search|WalK]-[SW|DivIB] [Pubmed|21219466]
  • Expression and Regulation

    [SW|Sigma factor]

  • ''[SW|spoVE]'': [protein|search|SigE] [Pubmed|8320223]
  • ''[protein|search|murG]'': [protein|search|SigM][Pubmed|18179421]
  • ''[SW|divIB]'': [protein|search|SigA] [Pubmed|8106328]
  • Biological materials

    FLAG-tag construct

  • GP2005 ''divIB-3xFLAG ermC'' (based on [SW|pGP1087]), available in [SW|Jörg Stülke]'s lab
  • References

  • 8459777,10852898,19429628,1391053,21219466,8320223,8106328,18179421,15659156,16936019,10217758,10792716,9720875,16936026,9426141,9044263