cell-division initiation protein (septum formation)
function
septum formation
product
cell-division protein
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|cell division], [SW|sporulation proteins], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|essential genes], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|SigM regulon], [SW|SpoIIID regulon]Gene
Coordinates on the chromosome (coding sequence)
1,593,704 -> 1,594,495
Phenotypes of a mutant
essential [Pubmed|12682299]The protein
Protein family
ftsQ family (according to Swiss-Prot)Structure
[PDB|2ALJ] (major extracytoplasmic domain, Geobacillus stearothermophilus)[SW|Localization]
cell membrane [Pubmed|9426141][SW|Interactions]
[protein|search|PbpB]-[SW|DivIB]-([protein|search|FtsL]-[SW|DivIC])2 [Pubmed|20870765], as part of the [SW|divisome][protein|search|WalK]-[SW|DivIB] [Pubmed|21219466]Expression and Regulation
[SW|Sigma factor]
''[SW|spoVE]'': [protein|search|SigE] [Pubmed|8320223]''[protein|search|murG]'': [protein|search|SigM][Pubmed|18179421]''[SW|divIB]'': [protein|search|SigA] [Pubmed|8106328]Biological materials
FLAG-tag construct
GP2005 ''divIB-3xFLAG ermC'' (based on [SW|pGP1087]), available in [SW|Jörg Stülke]'s labReferences
8459777,10852898,19429628,1391053,21219466,8320223,8106328,18179421,15659156,16936019,10217758,10792716,9720875,16936026,9426141,9044263