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divIB [2019-07-01 09:46:49]
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divIB [2019-07-01 09:46:49]

cell-division initiation protein (septum formation)
Locus
BSU15240
Isoelectric point
9.24
Molecular weight
30.02 kDa
Protein length
263 aa Sequence Blast
Gene length
792 bp Sequence Blast
Function
septum formation
Product
cell-division protein
Essential
yes
Synonyms
dds,tms-12

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,593,704 → 1,594,495

Phenotypes of a mutant

  • essential PubMed
  • The protein

    Protein family

  • FtsQ/DivIB family (according to UniProt)
  • Structure

  • 2ALJ (major extracytoplasmic domain, Geobacillus stearothermophilus)
  • Localization

  • cell membrane PubMed
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigM: sigma factor, (promoter within MurG) PubMed, in SigM regulon
  • SigA: sigma factor, PubMed, in SigA regulon
  • SigE: sigma factor, PubMed, in SigE regulon
  • Regulatory mechanism

  • SpoIIID: repression, PubMed, in SpoIIID regulon
  • Regulation

  • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed
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    Description

    Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon
  • Regulatory mechanism

  • stringent response: negative regulation, in stringent response
  • SpoIIID: repression, PubMed, in SpoIIID regulon
  • Regulation

  • expressed during vegatative growth PubMed
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    Description

    Regulation

  • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed
  • view in new tab

    Description

    Regulation

  • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed
  • view in new tab

    Biological materials

    FLAG-tag construct

  • GP2005 divIB-3xFLAG ermC (based on pGP1087), available in Jörg Stülke's lab
  • References

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