glgC [2017-8-11 16:0:3]

glucose-1-phosphate adenylyltransferase

locus: BSU30970

pI: 4.86

mw: 42.44 kDa

protein length: 380 aa

gene length: 1140 bp

function: glycogen biosynthesis

product: glucose-1-phosphate adenylyltransferase

essential: no

ec: 2.7.7.27

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.5|Biosynthesis of glycogen]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

Gene

Coordinates: 3,168,624 → 3,169,766

The protein

Catalyzed reaction/ biological activity

• ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose (according to Swiss-Prot)

Protein family

• bacterial/plant glucose-1-phosphate adenylyltransferase family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|63A4FD35A2E72C665BFA3F2632F06C7A0C954087|GlgD]

Structure

• [PDB|5L6S] (E. coli ADP-glucose pyrophosphorylase, 41% identity) [pubmed|27545622]

Expression and Regulation

Operons

• genes: [gene|52C8DE3C78B680C8883D1CD559CBC2D9ABFCC400|glgB]-[gene|B665735B76462724A3C7A1E89D3E613C18F21399|glgC]-[gene|63A4FD35A2E72C665BFA3F2632F06C7A0C954087|glgD]-[gene|EBEA85AD543B79C321CB5F28D1B7E1248640DC1D|glgA]-[gene|3AB4513126EFF54996A54CB7DEB6062C1A06AAC3|glgP]
  description: [Pubmed|8145641]

  sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|8145641], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

  regulation

  • expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|8145641]

References

• 8145641,27545622