SubtiBank SubtiBank
trmFO [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]
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trmFO [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

flavoprotein, tRNA:m(5)U-54 methyltransferase, glucose-inhibited division protein
locus
BSU16130
pI
5.77
mw
47.00 kDa
function
tRNA modification
product
tRNA:m(5)U-54 methyltransferase
essential
no
ec
2.1.1.74
synonyms
ylyC, gid
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]

    • [SW|Categories] containing this gene/protein

  • [SW|translation]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,685,812 -> 1,687,119

    The protein

    Catalyzed reaction/ biological activity

  • catalyzes the folate-dependent C(5)-methylation of uridine at position 54 in the TpsiC loop of tRNA

    • Protein family

  • TrmFO subfamily (according to Swiss-Prot)

    • [SW|Cofactors]

  • FAD, methylene-THF [Pubmed|24228791]

    • Structure

  • [PDB|3G5S] (TrmFO from ''Thermus thermophilus'', 54% identity, 79% similarity) [Pubmed|19416846]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • References

  • 16027442,20412857,21846722,24228791,21561081,23157377,23095745,19416846,24228791