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rpsH [Fri Jan 29 2016 17:26:57 GMT+0100 (CET)]
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rpsH [Fri Jan 29 2016 17:26:57 GMT+0100 (CET)]

ribosomal protein
locus
BSU01300
pI
10.00
mw
14.00 kDa
function
translation
product
ribosomal protein S8 (BS8)
essential
yes
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]
  • [category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|essential genes], [SW|universally conserved proteins], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|stringent response]
  • Gene

    Coordinates on the chromosome (coding sequence)
    141,974 -> 142,372

    Phenotypes of a mutant

  • essential [Pubmed|23002217,12682299]
  • The protein

    Protein family

  • [SW|ribosomal protein] S8P family (according to Swiss-Prot)
  • Modification

  • phosphorylated on Arg-72 [Pubmed|22517742]
  • Structure

  • [PDB|1SEI] (Geobacillus stearothermophilus)
  • Expression and Regulation

    Operon

  • ''[protein|search|rpsJ]-[protein|search|rplC]-[protein|search|rplD]-[protein|search|rplW]-[protein|search|rplB]-[protein|search|rpsS]-[protein|search|rplV]-[protein|search|rpsC]-[protein|search|rplP]-[protein|search|rpmC]-[protein|search|rpsQ]-[protein|search|rplN]-[protein|search|rplX]-[protein|search|rplE]-[protein|search|rpsN]-[protein|search|rpsH]-[protein|search|rplF]-[protein|search|rplR]-[protein|search|rpsE]-[protein|search|rpmD]-[protein|search|rplO]'' [Pubmed|9371452]
  • [SW|Sigma factor]

  • [protein|search|SigA] two promoters, about 140bp and 200bp upstream of the start codon [Pubmed|9371452]
  • Regulation

  • [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • References

  • 8635744,9371452,11948165,19653700,22517742,23002217