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ndk [Tue May 03 2016 10:03:48 GMT+0200 (CEST)]
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ndk [Tue May 03 2016 10:03:48 GMT+0200 (CEST)]

nucleoside diphosphate kinase
locus
BSU22730
pI
5.00
mw
16.00 kDa
function
maintainance of an equilibrium between the
concentrations of different nucleoside triphosphates
product
nucleoside diphosphate kinase
essential
no
ec
2.7.4.6
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.4|Nucleotide metabolism/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.6|Phosphorylation on a Thr residue]
  • [SW|Categories] containing this gene/protein

  • [SW|nucleotide metabolism/ other], [SW|phosphoproteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,381,354 -> 2,381,803

    Phenotypes of a mutant

  • inactivation of ''[SW|ndk]'' reduces sporulation efficiency to 13.4% that of wild type cells [Pubmed|26735940]
  • The protein

    Catalyzed reaction/ biological activity

  • ATP nucleoside diphosphate = ADP nucleoside triphosphate (according to Swiss-Prot)
  • Protein family

  • phosphate acetyltransferase and butyryltransferase family (according to Swiss-Prot)
  • Modification

  • phosphorylation on Thr-92 AND Ser-123 [Pubmed|17218307]
  • Structure

  • [PDB|1WKJ] (from ''Thermus thermophilus'', 59% identity, 82% similarity)
  • References

  • 17218307,26735940