function
arginine, ornithine and citrulline uptake
product
amino acid permease
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.4|APC superfamily][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.4|Biosynthesis/ acquisition of arginine][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.4|Utilization of arginine/ ornithine][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|transporters/ other], [SW|biosynthesis/ acquisition of amino acids], [SW|utilization of amino acids], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|AhrC regulon], [SW|CodY regulon], [SW|RocR regulon], [SW|SigL regulon], [SW|Spo0A regulon]Gene
Coordinates on the chromosome (coding sequence)
4,142,675 -> 4,144,078
The protein
Paralogous protein(s)
[protein|search|AapA], [protein|search|GabP], [protein|search|HutM], [protein|search|RocC], [protein|search|YbgF], [protein|search|YbxG], [protein|search|YdgF], [protein|search|YtnA], [protein|search|YvbW]Structure
[PDB|3LRB] (from ''E. coli'', 25% identity) [Pubmed|19478139][SW|Localization]
cell membrane (according to Swiss-Prot), membrane associated [Pubmed|18763711]Expression and Regulation
Operon
''[protein|search|rocD]-[protein|search|rocE]-[protein|search|rocF]'' [Pubmed|7540694][SW|Sigma factor]
[protein|search|SigL] [Pubmed|7540694]Regulation
induced by arginine ([protein|search|RocR], [protein|search|AhrC]) [Pubmed|7540694]repressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|12618455]Regulatory mechanism
[protein|search|RocR], [protein|search|AhrC]: transcription activation [Pubmed|7540694][SW|Spo0A]: transcription repression [Pubmed|14651647][protein|search|CodY]: transcription repression [Pubmed|12618455]References
14651647,12618455,18763711,7540694,19478139 
