SubtiBank SubtiBank
tcyC
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tcyC

cystine and diaminopimelate ABC transporter, ATP-binding protein
Locus
BSU_03590
Isoelectric point
7.19
Molecular weight
27.64 kDa
Protein length
247 aa Sequence Blast
Gene length
744 bp Sequence Blast
Function
cystine and diaminopimelate uptake
Product
cystine and diaminopimelate ABC transporter, ATP-binding protein
Essential
no
Synonyms
yckI

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
409,208 → 409,951

The protein

Catalyzed reaction/ biological activity

  • uptake of cystine and diaminopimelate PubMed
  • Protein family

  • ABC transporter superfamily (according to UniProt)
  • L-cystine importer (TC 3.A.1.3.14) family (single member, according to UniProt)
  • Paralogous protein(s)

    Domains

  • ABC transporter domain (aa 2-240) (according to UniProt)
  • Structure

  • 2Q0H (in complex with ADP-Mg2+, Geobacillus stearothermophilus, 55% identity)
  • Localization

  • attached to the membrane via TcyB PubMed
  • Expression and Regulation

    Operons

    Description

    Regulation

  • strongly repressed in response to glucose starvation in M9 medium PubMed
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    Biological materials

    Mutant

  • MGNA-C004 (yckI::erm), available at the NBRP B. subtilis, Japan
  • BKE03590 (ΔtcyC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AACGGTAAGCATACTCGGAA, downstream forward: _UP4_TAATAAGAAAAACAGAGCGT
  • BKK03590 (ΔtcyC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AACGGTAAGCATACTCGGAA, downstream forward: _UP4_TAATAAGAAAAACAGAGCGT
  • References

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