cccA [2017-04-24 15:34:12]

cytochrome c550

locus: BSU25190

pI: 5.28

mw: 12.63 kDa

protein length: 120 aa

gene length: 360 bp

function: respiration

product: cytochrome c550

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.4|Respiration/ other]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|CcpA regulon], [SW|AbrB regulon]

Gene

Coordinates: 2,599,523 → 2,599,885

The protein

[SW|Domains]

• transmembrane domain at the N-terminus (aa 5 -25) [Pubmed|2166045]

[SW|Cofactors]

• heme c [Pubmed|2166045]

[SW|Localization]

• cell membrane [Pubmed|2166045]

Expression and Regulation

Operons

• genes: [gene|B3EBB417FB2DE3CE6BAFB910E1913785C162EABF|cccA]
  description: [Pubmed|22383849]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|11361075], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

  regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, cre site overlaps -35 region of the promoter [Pubmed|11361075], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

  regulation

  • carbon catabolite repression ([protein|search|CcpA]) [Pubmed|22900538,11361075,12850135]

  additional information

  • the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]

References

• 2171986,10024472,12884008,8383048,2166045,12850135,11361075,22900538,22900538,22383849,20817675,10473570