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cotZ [Fri Jun 24 2016 13:49:38 GMT+0200 (CEST)]
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cotZ [Fri Jun 24 2016 13:49:38 GMT+0200 (CEST)]

spore crust protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat
locus
BSU11740
pI
5.00
mw
16.00 kDa
function
spore crust assembly
product
spore crust protein (insoluble fraction)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.3|Class III]
  • [SW|Categories] containing this gene/protein

  • [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|GerE regulon], [SW|GerR regulon], [SW|SigE regulon], [SW|SigK regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,249,442 -> 1,249,888

    Phenotypes of a mutant

  • mis-assembly of the spore crust [Pubmed|22171814]
  • The protein

    Paralogous protein(s)

  • [SW|CotY]
  • [SW|Localization]

  • outermost layer of the spore coat (crust), localization depends on [protein|search|CotE] [Pubmed|22171814]
  • more abundant at the mother cell-proximal pole of the forespore [Pubmed|19933362,21665972]
  • [SW|Interactions]

  • [protein|search|CotY]-[protein|search|CotZ] [Pubmed|19304857,26341943]
  • [protein|search|CotZ] is required for the proper spore crust localization of [protein|search|CotY] [Pubmed|21665972]
  • Expression and Regulation

    Operon

  • ''[protein|search|cotY]-[protein|search|cotZ]'' [Pubmed|7519271]
  • [SW|Sigma factor]

  • [protein|search|SigK] [Pubmed|7519271,15699190], [protein|search|SigE] [Pubmed|15383836]
  • Regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|7519271,15699190]
  • Regulatory mechanism

  • [protein|search|GerE]: transcription activation [Pubmed|7519271]
  • [protein|search|GerR]: transcription activation [Pubmed|15621419]
  • References

    Reviews

  • 22192522,23202530,27227299
  • Original publications

  • 19304857,7519271,15699190,19933362,20451384,21665972,22171814,15383836,26341943,15621419