SubtiBank SubtiBank
ahpA
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ahpA

alkyl hydroperoxide reductase
Locus
BSU_14220
Isoelectric point
4.49
Molecular weight
20.30 kDa
Protein length
180 aa Sequence Blast
Gene length
543 bp Sequence Blast
Function
protection against peroxide stress
Product
alkyl hydroperoxide reductase
Essential
no
Synonyms
ykuU
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Electron transport and ATP synthesis → Electron transport/ other/ based on similarity

    • Gene

    Coordinates
    1,492,261 → 1,492,803

    The protein

    Catalyzed reaction/ biological activity

  • [protein]-dithiol + hydroperoxide --> [protein]-disulfide + alcohol + H2O (according to UniProt)

    • Protein family

  • peroxiredoxin family (according to UniProt)

    • Paralogous protein(s)

  • AhpC

    • Domains

  • Thioredoxin domain (aa 4-165) (according to UniProt)

    • Structure

  • 4XCS (human peroxiredoxin, 48% identity)

    • Expression and Regulation

    Operons

    Genes
    ahpA-ahpT
    Description
    PubMed

    Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
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    Biological materials

    Mutant

  • GP1729 ahpAT::kan trpC2 available at Jörg Stülkes lab
  • MGNA-B343 (ykuU::erm), available at the NBRP B. subtilis, Japan
  • BKE14220 (ΔahpA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGTATCCCTCCAATTT, downstream forward: _UP4_TAATTCTTTCCAAGAACGAA
  • BKK14220 (ΔahpA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGTATCCCTCCAATTT, downstream forward: _UP4_TAATTCTTTCCAAGAACGAA

    • References

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