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spoVAC [Wed Jan 06 2016 13:30:15 GMT+0100 (CET)]
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spoVAC [Wed Jan 06 2016 13:30:15 GMT+0100 (CET)]

mechanosensitive channel, essential for the uptake of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2 ) into developing spores, required for spore maturation
locus
BSU23420
pI
9.00
mw
15.00 kDa
function
spore maturation
product
mechanosensitive channel
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.7|Coping with hypo-osmotic stress]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|sporulation proteins], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|SigG regulon], [SW|SpoVT regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    2,441,804 -> 2,442,256

    Expression and Regulation

    Operon

  • ''[SW|spoVAA]-[SW|spoVAB]-[SW|spoVAC]-[SW|spoVAD]-[SW|spoVAEB]-[SW|spoVAEA]-[SW|spoVAF]-[protein|search|lysA]'' [Pubmed|7934830]

    • [SW|Sigma factor]

  • [protein|search|SigG] [Pubmed|15699190,1903432]

    • Regulation

  • expressed late during sporulation in the forespore ([protein|search|SigG], [SW|SpoVT]) [Pubmed|15699190,1903432,8755877]

    • Regulatory mechanism

  • [SW|SpoVT]: transcription activation [Pubmed|8755877]

    • Labs working on this gene/protein

  • [SW|Peter Setlow], University of Connecticut Health Center, USA

    • References

  • 3114420,11751839,15451103,3926949,17158659,6432957,7934830,15699190,1903432,8755877,22328679,21398556,24666282,24752279