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prp [Mon Feb 13 2017 09:42:37 GMT+0100 (CET)]
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prp [Mon Feb 13 2017 09:42:37 GMT+0100 (CET)]

protein cysteine protease, required for N-terminal cleavage of ribosomal protein L27
locus
BSU27950
pI
4.00
mw
12.00 kDa
function
maturation of ribosomal protein L27
product
L27 protein cysteine protease
essential
no
synonyms
ysxB

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.6|Ribosome assembly]
  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|proteolysis]
  • This gene is a member of the following [SW|regulons]

  • [SW|stringent response]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,855,177 -> 2,855,515

    The protein

    Catalyzed reaction/ biological activity

  • N-terminal cleavage of ribosomal protein [rpmA|search|L27] [Pubmed|25388641]
  • Structure

  • [PDB|2P92] (the protein from ''S. aureus'')
  • Expression and Regulation

    Operon

  • ''[SW|spoIVFA]-[SW|spoIVFB]-[protein|search|rplU]-[protein|search|prp]-[protein|search|rpmA]'' [Pubmed|22383849]
  • ''[protein|search|rplU]-[protein|search|prp]-[protein|search|rpmA]'' [Pubmed|22383849]
  • Regulation

  • [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • References

  • 11948165,25388641,22383849,28187498