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prp [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]
protein cysteine protease, required for N-terminal cleavage of ribosomal protein L27
function
maturation of rpmA|L27
product
L27 protein cysteine protease
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.6|Ribosome assembly][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][SW|Categories] containing this gene/protein
[SW|translation], [SW|proteolysis]This gene is a member of the following [SW|regulons]
[SW|stringent response]Gene
Coordinates on the chromosome (coding sequence)
2,855,177 -> 2,855,515
The protein
Catalyzed reaction/ biological activity
N-terminal cleavage of ribosomal protein [rpmA|search|L27] [Pubmed|25388641]Structure
[PDB|2P92] (the protein from ''S. aureus'')Expression and Regulation
Operon
''[SW|spoIVFA]-[SW|spoIVFB]-[protein|search|rplU]-[protein|search|prp]-[protein|search|rpmA]'' [Pubmed|22383849]''[protein|search|rplU]-[protein|search|prp]-[protein|search|rpmA]'' [Pubmed|22383849]Regulation
[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]References
11948165,25388641,22383849 
