SubtiBank SubtiBank
yueD [2019-04-16 13:35:03]
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yueD [2019-04-16 13:35:03]

similar to sepiapterin reductase
locus
BSU31840
pI
6.43
mw
26.96 kDa
protein length
243 aa Sequence Blast
gene length
732 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    3,265,406 → 3,266,137

    The protein

    Catalyzed reaction/ biological activity

  • 2-hydroxy-1,2-diphenylethanone + NADP+ = 1,2-diphenylethane-1,2-dione + NADPH (according to Swiss-Prot)

    • Protein family

  • short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

    • Structure

  • [PDB|5IF3] (from Burkholderia Vietnamiensis 34% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|B258CA26B0EC2310475FCCD67F1F196857FC0004|yueD]
    description
    [Pubmed|22383849]
    view in new tab

    genes
    [gene|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE]-[gene|3CC3E197848E9688413C15CEA7DDCF0A7120A920|yukD]-[gene|3FE4A91C7D0B43C8704391F2F9493852B3AED9B0|yukC]-[gene|6007664F3D979B4D8D4662C7F6E5CF2F489268E3|yukB]-[gene|0A38B2E900532C9950DE6E629F5EB21D64E18B55|yueB]-[gene|DA52C4CD130F32734E01A52F2F395127D2260F61|yueC]-[gene|B258CA26B0EC2310475FCCD67F1F196857FC0004|yueD]
    description
    [Pubmed|22383849]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|22383849], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU]: activation, [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU]-P, [Pubmed|23861817], in [regulon|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU regulon]

    • regulation

  • expressed in the stationary phase [Pubmed|23861817]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B564 (yueD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1563 NBRP B. subtilis, Japan]
  • BKE31840 (Δ[gene|B258CA26B0EC2310475FCCD67F1F196857FC0004|yueD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE31840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGGAAACCTCCTTTTCC, downstream forward: _UP4_TAGAGCAGATATTTTCTGCT
  • BKK31840 (Δ[gene|B258CA26B0EC2310475FCCD67F1F196857FC0004|yueD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK31840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGGAAACCTCCTTTTCC, downstream forward: _UP4_TAGAGCAGATATTTTCTGCT