adhR [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

transcriptional activator (MerR family) of adhA-yraA, responsive to formaldehyde and methylglyoxal

locus: BSU27000

pI: 9.64

mw: 16.00 kDa

function: regulation of the protective response to formaldehyde and methylglyoxal

product: transcriptional activator (MerR family)

essential: no

synonyms: yraB

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[SW|Categories] containing this gene/protein

• [SW|transcription factors and their control], [SW|resistance against oxidative and electrophile stress]

Gene

Coordinates on the chromosome (coding sequence): 2,755,382 -> 2,755,804

The protein

Protein family

• [SW|MerR family]

Modification

• activity probably redox-controlled via thiol-(S)-alkylation at Cys-52 by aldehydes [Pubmed|19170879]

[SW|Localization]

• cytoplasmic

Labs working on this gene/protein

• [SW|Haike Antelmann],University of Greifswald, Germany

References

• 21722790