pabB [Tue Feb 09 2016 20:11:55 GMT+0100 (CET)]

para-aminobenzoate synthase (subunit A)

locus: BSU00740

pI: 5.00

mw: 53.00 kDa

function: biosynthesis of folate

product: para-aminobenzoate synthase (subunit A)

essential: no

ec: 2.6.1.85

synonyms: pab

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.5|Biosynthesis of folate]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of cofactors]

Gene

Coordinates on the chromosome (coding sequence): 82,864 -> 84,276

The protein

Catalyzed reaction/ biological activity

• Chorismate L-glutamine = 4-amino-4-deoxychorismate L-glutamate (according to Swiss-Prot)

Protein family

• anthranilate synthase component I family (according to Swiss-Prot)

Structure

• [PDB|5CWA] (from ''Mycobacterium tuberculosis'', 39% identity)

[SW|Interactions]

• [protein|search|PabA]-[protein|search|PabB]

Expression and Regulation

Operon

• ''[protein|search|pabB]-[protein|search|pabA]-[protein|search|pabC]-[protein|search|sul]-[protein|search|folB]-[protein|search|folK]-[protein|search|yazB]-[protein|search|yacF]-[protein|search|lysS]'' [Pubmed|9084182]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|9084182]

References

• 9084182