ureB [Mon Aug 31 2015 13:57:14 GMT+0200 (CEST)]

urease (beta subunit)

Locus: BSU36650

Isoelectric point: 9.75

Molecular weight: 13.00 kDa

Function: utilization of urea as alternative nitrogen source

Product: urease (beta subunit)

Essential: no

E.C.: 3.5.1.5

Synonyms

Genomic Context

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Categories containing this gene/protein

• Metabolism → Amino acid/ nitrogen metabolism → Utilization of nitrogen sources other than amino acids → Utilization of urea

Categories containing this gene/protein

• utilization of nitrogen sources other than amino acids

This gene is a member of the following regulons

• CodY regulon, GlnR regulon, PucR regulon, SigH regulon, TnrA regulon

The protein

Catalyzed reaction/ biological activity

• Urea + H₂O = CO₂ + 2 NH₃ (according to Swiss-Prot)

Protein family

• urease beta subunit family (according to Swiss-Prot)

Localization

• cytoplasm (according to Swiss-Prot)

Interactions

• UreA-UreB-UreC

Expression and Regulation

Operon

• ureA-ureB-ureC PubMed

Sigma factor

• SigA PubMed, SigH PubMed

Regulation

• induced by nitrogen limitation (GlnR, TnrA) PubMed
• induced in the presence of purine nucleotides (inducer: allantoin) (PucR) PubMed
• repressed during growth in the presence of branched chain amino acids (CodY) PubMed

Regulatory mechanism

• GlnR: transcription repression PubMed
• TnrA: transcription activation PubMed
• PucR: transcription activation PubMed
• CodY: transcription repression PubMed

References

Reviews

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Original publications

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