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cwlD [Mon Aug 31 2015 13:52:02 GMT+0200 (CEST)]
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cwlD [Mon Aug 31 2015 13:52:02 GMT+0200 (CEST)]

N-acetylmuramoyl-L-alanine amidase, spore cortex peptidoglycan synthesis
locus
BSU01530
pI
9.79
mw
26.00 kDa
function
spore cortex peptidoglycan synthesis
product
N-acetylmuramoyl-L-alanine amidase
essential
no
ec
3.5.1.28
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|cell wall/ other], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|LexA regulon], [SW|SigE regulon], [SW|SigG regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • formation of muramic acid delta-lacton in spore cortex peptidoglycan [Pubmed|14679227]
  • Protein family

  • N-acetylmuramoyl-L-alanine amidase 3 family (according to Swiss-Prot)
  • [SW|Domains]

  • contains an amidase_3 domain (like [protein|search|CwlC], [protein|search|LytC], [protein|search|YqiI], [protein|search|YrvJ])
  • [SW|Localization]

  • secreted (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|ybaK]-[protein|search|cwlD]'' [Pubmed|7559346]
  • ''[protein|search|cwlD]'' [Pubmed|7559346]
  • [SW|Sigma factor]

  • [protein|search|SigE] [Pubmed|15699190]
  • ''[protein|search|ybaK]'': [protein|search|SigG] [Pubmed|7559346]
  • ''[protein|search|cwlD]'': [protein|search|SigE] [Pubmed|7559346]
  • Regulation

  • expressed during sporulation ([protein|search|SigG], [protein|search|SigE]) [Pubmed|7559346]
  • repressed when no DNA damage is present ([protein|search|LexA]) [Pubmed|16267290]
  • Regulatory mechanism

  • [protein|search|LexA]: transcription repression [Pubmed|16267290]
  • References

  • 12646705,10498740,7559346,14679227,16267290,22123250,24405365