N-acetylmuramoyl-L-alanine amidase, spore cortex peptidoglycan synthesis
function
spore cortex peptidoglycan synthesis
product
N-acetylmuramoyl-L-alanine amidase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|cell wall/ other], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|LexA regulon], [SW|SigE regulon], [SW|SigG regulon]The protein
Catalyzed reaction/ biological activity
formation of muramic acid delta-lacton in spore cortex peptidoglycan [Pubmed|14679227]Protein family
N-acetylmuramoyl-L-alanine amidase 3 family (according to Swiss-Prot)[SW|Domains]
contains an amidase_3 domain (like [protein|search|CwlC], [protein|search|LytC], [protein|search|YqiI], [protein|search|YrvJ])[SW|Localization]
secreted (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|ybaK]-[protein|search|cwlD]'' [Pubmed|7559346]''[protein|search|cwlD]'' [Pubmed|7559346][SW|Sigma factor]
[protein|search|SigE] [Pubmed|15699190]''[protein|search|ybaK]'': [protein|search|SigG] [Pubmed|7559346]''[protein|search|cwlD]'': [protein|search|SigE] [Pubmed|7559346]Regulation
expressed during sporulation ([protein|search|SigG], [protein|search|SigE]) [Pubmed|7559346]repressed when no DNA damage is present ([protein|search|LexA]) [Pubmed|16267290]Regulatory mechanism
[protein|search|LexA]: transcription repression [Pubmed|16267290]References
12646705,10498740,7559346,14679227,16267290,22123250,24405365