bglC [2017-8-11 16:0:3]

endo-1,4-beta-glucanase

locus: BSU18130

pI: 8.62

mw: 55.12 kDa

protein length: 499 aa

gene length: 1497 bp

function: beta-1,4-glucan degradation

product: endo-1,4-beta-glucanase)

essential: no

ec: 3.2.1.4

synonyms: eglS

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.27|Utilization of other polymeric carbohydrates]
• [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]

Gene

Coordinates: 1,940,625 → 1,942,124

The protein

Catalyzed reaction/ biological activity

• Endohydrolysis of (1→4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans (according to Swiss-Prot)

Protein family

• glycosyl hydrolase 5 (GH5) (cellulase A) family (according to Swiss-Prot)

Structure

• [PDB|3PZT] [Pubmed|21880019]

[SW|Localization]

• extracellular (signal peptide) [Pubmed|18957862]

Expression and Regulation

Operons

• genes: [gene|B0528C4772B2357D10AEEA3C63080C5176B27E7B|bglC]
  description: [pubmed|22383849]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|3106328], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

Biological materials

Mutant

• 1A751 (no resistance), [Pubmed|7704256], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A751&Search=1A751 BGSC]
• 1A752 (no resistance), [Pubmed|7704256], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A752&Search=1A752 BGSC]
• 1A976 (no resistance), [Pubmed|21255377], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A976&Search=1A976 BGSC]

References

• 18957862,3024130,21880019,3106328,23543074,27334041