SubtiBank SubtiBank
yvcT
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yvcT

similar to hydroxypyruvate reductase
Locus
BSU_34680
Isoelectric point
5.09
Molecular weight
36.46 kDa
Protein length
325 aa Sequence Blast
Gene length
978 bp Sequence Blast
Function
unknown
Product
unknown
Essential
no
E.C.
1.1.1.215
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Groups of genes → Proteins of unknown function

    • Gene

    Coordinates
    3,562,566 → 3,563,543

    The protein

    Catalyzed reaction/ biological activity

  • D-gluconate + NADP+ --> 2-dehydro-D-gluconate + H+ + NADPH (according to UniProt)

    • Protein family

  • D-isomer specific 2-hydroxyacid dehydrogenase family (with YoaD and SerA, according to UniProt)

    • Structure

  • 5AOV (from Pyrococcus furiosus, 46% identity) PubMed

    • Additional information

  • The gene is annotated in KEGG as gluconate 2-dehydrogenase EC 1.1.1.215. The gene is marked “similar to glycerate dehydrogenase” in MetaCyc and marked as probable EC 1.1.1.215 in Swiss-Prot. No literature/experimental evidence supporting the annotation is available. PubMed

    • Expression and Regulation

    Operons

    Genes
    yvcT
    Description
    PubMed
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    Biological materials

    Mutant

  • MGNA-B633 (yvcT::erm), available at the NBRP B. subtilis, Japan
  • BKE34680 (ΔyvcT::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGGCTCCCCCTTTATGGC, downstream forward: _UP4_TAAATCAAAAATCCGGTCTG
  • BKK34680 (ΔyvcT::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGGCTCCCCCTTTATGGC, downstream forward: _UP4_TAAATCAAAAATCCGGTCTG

    • References

    Research papers

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