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spoVAB
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spoVAB

essential for the uptake of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2+) into developing spores, required for spore maturation
locus
BSU_23430
pI
10.12
mw
15.08 kDa
protein length
141 aa Sequence Blast
gene length
426 bp Sequence Blast
function
spore maturation
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    2,442,269 → 2,442,694

    The protein

    [SW|Localization]

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|5410018998EC9792A69CF0D9C438EEF5AC8A82C5|spoVAA]-[gene|AEC70413BDC29F435776D532E7049AA9A0BD893D|spoVAB]-[gene|B280951A232E941FB0A6C8834049765BE1E16437|spoVAC]-[gene|9531F0A0DC4AE5696FFBAC9C2A773F15840E3255|spoVAD]-[gene|31D6CB7EC20C39C1815CA4552B8B9C4BE304E86B|spoVAEB]-[gene|B44529B69769D7AF1010E06C95E398EA91A3E798|spoVAEA]-[gene|CBE5093DFBBCE25071CCE12408BC9AFF7A158C03|spoVAF]-[gene|02F1C926D200DE85C93A0ACEF23AD25FBD12B0BD|lysA]
    description
    [Pubmed|7934830]

    sigma factors

  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG]: sigma factor, [Pubmed|15699190,1903432], in [regulon|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG regulon]

    • regulatory mechanism

  • [protein|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|SpoVT]: activation, [Pubmed|8755877], in [regulon|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|SpoVT regulon]

    • regulation

  • expressed late during sporulation in the forespore ([protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG], [SW|SpoVT]) [Pubmed|15699190,1903432,8755877]
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    Biological materials

    Mutant

  • BKE23430 (Δ[gene|AEC70413BDC29F435776D532E7049AA9A0BD893D|spoVAB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCCGACAAAAATGATGAACA, downstream forward: _UP4_GACCATTCATAAGGAGGTTT
  • BKK23430 (Δ[gene|AEC70413BDC29F435776D532E7049AA9A0BD893D|spoVAB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCCGACAAAAATGATGAACA, downstream forward: _UP4_GACCATTCATAAGGAGGTTT

    • labs

  • [SW|Peter Setlow], University of Connecticut Health Center, USA

    • References

  • 3114420,11751839,15451103,3926949,17158659,6432957,7934830,15699190,1903432,8755877,22328679,21398556