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trpB [Fri Dec 04 2015 20:39:41 GMT+0100 (CET)]
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trpB [Fri Dec 04 2015 20:39:41 GMT+0100 (CET)]

tryptophan synthase (beta subunit)
Locus
BSU22640
Isoelectric point
5.00
Molecular weight
43.00 kDa
Function
biosynthesis of tryptophan
Product
tryptophan synthase (beta subunit)
Essential
no
E.C.
4.2.1.20
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Categories containing this gene/protein

This gene is a member of the following regulons

Gene

Coordinates on the chromosome (coding sequence)
2,372,304 -> 2,373,506

The protein

Catalyzed reaction/ biological activity

  • L-serine 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan glyceraldehyde 3-phosphate H2O (according to Swiss-Prot)
  • Interactions

    Expression and Regulation

    Operon

    Sigma factor

    Regulation

  • not expressed if tryptophan is available ([MtrB|search|TRAP]) PubMed
  • Regulatory mechanism

  • [MtrB|search|TRAP]: binding to the mRNA in the presence of tryptophan, this results in transcription termination PubMed
  • Additional information

  • the mRNA of the trpE-trpD-trpC-trpF-trpB-trpA-hisC-tyrA-aroE operon strongly accumulates upon depletion of [rny|search|RNase Y] PubMed
  • the mRNA is substantially stabilized upon depletion of [Rny|search|RNase Y] PubMed
  • References

    Reviews

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    Original publications

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