sipV [Mon Aug 31 2015 13:53:30 GMT+0200 (CEST)]

signal peptidase I

Locus: BSU10490

Isoelectric point: 10.00

Molecular weight: 18.00 kDa

Function: protein secretion

Product: signal peptidase I

Essential: no

Synonyms: yhjF

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Protein secretion
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• protein secretion, membrane proteins

This gene is a member of the following regulons

• LexA regulon

Gene

Coordinates on the chromosome (coding sequence): 1,122,175 -> 1,122,681

The protein

Catalyzed reaction/ biological activity

• Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins (according to Swiss-Prot)

Protein family

• peptidase S26 family (according to Swiss-Prot)

Paralogous protein(s)

• SipS, SipT, SipU

Localization

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• yhjE-sipV (according to DBTBS)

Regulation

• induced upon DNA damage (LexA) PubMed

Regulatory mechanism

• LexA: transcription repression PubMed

Labs working on this gene/protein

• Jan Maarten van Dijl, Groningen, Netherlands

References

Reviews

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Original publications

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