bmr [Mon Aug 31 2015 13:55:29 GMT+0200 (CEST)]

general stress protein, multidrug-efflux transporter

Locus: BSU24010

Isoelectric point: 9.70

Molecular weight: 42.00 kDa

Function: multidrug resistance

Product: multidrug-efflux transporter

Essential: no

Synonyms: bmr1

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → Transporters/ other → Other exporters
• Lifestyles → Coping with stress → General stress proteins (controlled by SigB)
• Lifestyles → Coping with stress → Resistance against toxins/ antibiotics
• Groups of genes → Membrane proteins

Syns: bmr1

Categories containing this gene/protein

• transporters/ other, general stress proteins (controlled by SigB), resistance against toxins/ antibiotics

This gene is a member of the following regulons

• BmrR regulon, Mta regulon, SigB regulon

The protein

Protein family

• TCR/tet family (according to Swiss-Prot)

Paralogous protein(s)

• Blt

Expression and Regulation

Operon

• bmrU-bmr-bmrR PubMed
• bmr-bmrR PubMed

Sigma factor

• bmrU: SigB PubMed
• bmr: SigA PubMed

Regulation

• bmrU: induced by stress (SigB) PubMed
• bmr: induced by rhodamine 6G and tetraphenylphosphonium (BmrR) PubMed

Regulatory mechanism

• BmrR: transcription activation PubMed
• Mta: transcription activation PubMed

References

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