general stress protein, multidrug-efflux transporter
function
multidrug resistance
product
multidrug-efflux transporter
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.11|Other exporters][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|transporters/ other], [SW|general stress proteins (controlled by SigB)], [SW|resistance against toxins/ antibiotics]This gene is a member of the following [SW|regulons]
[SW|BmrR regulon], [SW|Mta regulon], [SW|SigB regulon]The protein
Protein family
TCR/tet family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|Blt]Expression and Regulation
Operon
''[protein|search|bmrU]-[protein|search|bmr]-[protein|search|bmrR]'' [Pubmed|10220166]''[protein|search|bmr]-[protein|search|bmrR]'' [Pubmed|7961792][SW|Sigma factor]
''[protein|search|bmrU]'': [protein|search|SigB] [Pubmed|11544224]''[protein|search|bmr]'': [protein|search|SigA] [Pubmed|10200972]Regulation
''[protein|search|bmrU]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]''[protein|search|bmr]'': induced by rhodamine 6G and tetraphenylphosphonium ([protein|search|BmrR]) [Pubmed|7961792]Regulatory mechanism
[protein|search|BmrR]: transcription activation [Pubmed|7961792][protein|search|Mta]: transcription activation [Pubmed|10200972]References
7608059,10220166,11544224,10200972,7961792,20230832,25756668 
