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folB
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folB

dihydroneopterin aldolase
Locus
BSU_00780
Isoelectric point
5.23
Molecular weight
13.38 kDa
Protein length
120 aa Sequence Blast
Gene length
363 bp Sequence Blast
Function
biosynthesis of folate
Product
dihydroneopterin aldolase
Essential
yes
E.C.
4.1.2.25
Synonyms
folA,yacE

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
86,587 86,949

Phenotypes of a mutant

  • essential PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • 7,8-dihydroneopterin --> 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde (according to UniProt)
  • Protein family

  • DHNA family (single member, according to UniProt)
  • Structure

  • 1U68 (from Staphylococcus aureus, 47% identity, 72% similarity) PubMed
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulation

  • translation repressed by tryptophan (MtrB) PubMed
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    References

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