mrpB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

Na+/H+ antiporter subunit, multiple resistance and pH homeostasis

locus: BSU31610

pI: 4.91

mw: 15.00 kDa

function: sodium export

product: Na+/H+ antiporter subunit

essential: yes

synonyms: yufU

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.2|Sodium uptake/ export]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|metal ion homeostasis (K, Na, Ca, Mg)], [SW|essential genes], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 3,248,996 -> 3,249,427

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

[SW|Localization]

• cell membrane (according to Swiss-Prot)

[SW|Interactions]

• [protein|search|MrpA]-[protein|search|MrpB]-[protein|search|MrpC]-[protein|search|MrpD]-[protein|search|MrpE]-[protein|search|MrpF]-[protein|search|MrpG] (complex)

Expression and Regulation

Operon

• ''[protein|search|mrpA]-[protein|search|mrpB]-[protein|search|mrpC]-[protein|search|mrpD]-[protein|search|mrpE]-[protein|search|mrpF]-[protein|search|mrpG]'' [Pubmed|9274030,10198001]

Biological materials

Mutant

• SM-GN9 (mrpB-spc), available in [SW|Anne Galinier]'s and [SW|Boris Görke]'s labs

References

• 11004162,9274030,10198001,19389778,17693497